Thermo Fisher Scientific ZNF408 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 Rabbit Polyclonal 항체로 Western blot에 적합. 항원 친화 크로마토그래피로 정제되어 순도 95% 이상. PBS 및 glycerol 기반 용액 형태로 제공되며 장기 보관 시 -20°C 권장. 연구용으로만 사용 가능.
- 카탈로그번호
- PA576410
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein of human ZNF408 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2720137 |
Product Specific Information
The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen. The purity is >95% (by SDS-PAGE).
Target Information
Zinc-finger proteins contain DNA-binding domains and have diverse functions, including transcriptional activation and repression. Most zinc-finger proteins feature Kruppel-type DNA binding and KRAB domains that interact with KAP1 to recruit histone-modifying proteins.
ZNF408, a member of the Kruppel C2H2-type zinc-finger protein family, is encoded on human chromosome 11, which includes over 1,400 genes and accounts for nearly 4% of the human genome. Mutations in genes located on chromosome 11 are associated with disorders such as Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema, and Smith-Lemli-Opitz syndrome.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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