Thermo Fisher Scientific CD44v6 Monoclonal Antibody (VFF-7), FITC
CD44v6 변이형을 인식하는 FITC 결합 단클론 항체로, 인간 시료에서 IHC 및 유세포분석(Flow Cytometry)에 적합합니다. 마우스 IgG1 형식이며, 4°C 암소 보관이 필요합니다. CD44 관련 세포 접착 및 이동 연구에 활용됩니다.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: Assay-dependent
Flow Cytometry (Flow)
- Tested Dilution: Assay-dependent
- Publications: 1 publication available
Miscellaneous PubMed (Misc)
- Publications: 1 publication available
Product Specifications
| 항목 | 내용 |
|---|---|
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Recommended Isotype Control | Mouse IgG1 kappa Isotype Control (P3.6.2.8.1), FITC, eBioscience™ |
| Class | Monoclonal |
| Type | Antibody |
| Clone | VFF-7 |
| Immunogen | Recognizes variant portion of CD44 encoded by exon v6. CD44 v6 expression limited to activated lymphocytes and macrophages. |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Storage Conditions | 4°C, store in dark |
| Shipping Conditions | Wet ice |
| RRID | AB_2536368 |
Additional Formats
- Unconjugated
- Biotin
- Request custom conjugation
Target Information
CD44 cell surface antigen is a 100 kDa glycoprotein widely expressed on human leukocytes, white matter of the brain, and some epithelial cells of the intestine and breast. Several isoforms of CD44 exist, including the predominant CD44H isoform detected in many normal tissues.
CD44 functions as a receptor for hyaluronic acid (HA) and is involved in cell-cell interactions, adhesion, and migration. It participates in lymphocyte activation, recirculation, and homing. CD44 expression may be up-regulated in certain carcinomas, potentially related to metastatic potential.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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