Thermo Fisher Scientific USP6 Polyclonal Antibody
Thermo Fisher Scientific의 USP6 Polyclonal Antibody는 인간 USP6 단백질을 표적으로 하는 토끼 유래 IgG 항체로, Western blot에서 검증됨. 합성 펩타이드 면역원 기반으로 제작되어 높은 특이성과 재현성을 제공. 연구용으로만 사용 가능.
- 카탈로그번호
- PA544968
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): Tested dilution 1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the C-terminal of human USP6 (aa 1292–1341) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2608927 |
Product Specific Information
- Peptide sequence: NHSEEDSTDD QREDTHIKPI YNLYAISCHS GILSGGHYIT YAKNPNCKWY
- Sequence homology:
Cow: 93%
Dog: 93%
Guinea Pig: 100%
Horse: 93%
Human: 100%
Mouse: 93%
Rabbit: 91%
Rat: 100%
Target Information
USP6 is a deubiquitinase with ATP-independent isopeptidase activity, cleaving at the C-terminus of the ubiquitin moiety and catalyzing its own deubiquitination. Isoform 2 shows deubiquitinating activity in vitro, while isoform 3 does not. USP6 promotes plasma membrane localization of ARF6 and selectively regulates ARF6-dependent endocytic protein trafficking. It can initiate tumorigenesis by inducing matrix metalloproteinase production following NF-kappa-B activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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