
Thermo Fisher Scientific 5HT2B Receptor/SR-2B Polyclonal Antibody
5HT2B Receptor/SR-2B에 특이적인 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF, ELISA 등 다양한 응용 가능. Human 시료 반응성. Protein A로 정제된 액상 항체로 -20°C 보관. 연구용으로만 사용.
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Thermo Fisher Scientific 5HT2B Receptor/SR-2B Polyclonal Antibody
Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human 5HT2B Receptor/SR-2B, amino acids 1–100 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
HTR2B is a G-protein coupled receptor for 5-hydroxytryptamine (serotonin). It functions as a receptor for various ergot alkaloid derivatives and psychoactive substances. Ligand binding causes a conformational change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of downstream effectors. HTR2B also plays a role in pain perception and behavior regulation. It is required for normal proliferation of embryonic cardiac myocytes and normal heart development.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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