Thermo Fisher Scientific CD4 Monoclonal Antibody (YTS191.1), PE
Flow Cytometry용 CD4 단클론 항체로, Rat IgG2b 아이소타입의 YTS191.1 클론입니다. PE 형광체로 결합되어 있으며, 마우스 시료에 반응합니다. 단백질 G로 정제되어 있으며 4°C에서 보관합니다.
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Applications
- Flow Cytometry (Flow): Assay-dependent
- Publications: 7 publications available
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Mouse |
| Published Species | Mouse |
| Host / Isotype | Rat / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | YTS191.1 |
| Immunogen | Murine thymocytes |
| Conjugate | PE (R-Phycoerythrin) |
| Excitation / Emission Max | 565 / 576 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538834 |
Additional Formats
- Biotin (Cat. No. MA5-17440)
- FITC (Cat. No. MA5-17442)
- Custom conjugation available upon request
Target Information
The CD4 antigen is involved in the recognition of MHC class II molecules and serves as a co-receptor for HIV. CD4 is primarily expressed on T helper cells but may also be found on monocytes, macrophages, and dendritic cells. It is expressed in thymus, lymph nodes, tonsils, spleen, and certain regions of the brain and gut. CD4 functions in T-cell activation through association with the T-cell receptor complex and protein tyrosine kinase Lck. It may also mediate neuronal damage in immune-related CNS diseases. Multiple alternatively spliced transcripts have been identified (RefSeq, July 2017).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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