Thermo Fisher Scientific AMPK gamma-1,2,3 Polyclonal Antibody
AMPK gamma-1,2,3 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체입니다. Western blot에 적합하며, 지방산 및 콜레스테롤 합성 조절 연구에 활용됩니다. 액상 형태로 제공되며 -20°C에서 보관합니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic peptide derived from the internal region of human PRKAG1/2/3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2555225 |
Target Information
The 5-AMP activated protein kinase (AMPK), a member of the SNF1 (sucrose non fermentor) kinase family, is a heterotrimeric protein composed of alpha (63 kDa), beta (30 kDa), and gamma (38 kDa) subunits.
The alpha subunit serves as the catalytic subunit, while the beta and gamma subunits are non-catalytic but interact with the active subunit in liver.
AMPK regulates fatty acid and sterol synthesis by phosphorylation of acetyl-CoA carboxylase and cholesterol synthesis via phosphorylation and inactivation of hydroxymethylglutaryl-CoA reductase.
It is activated by AMP and can also be regulated by treatment with purified protein phosphatase in vitro.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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