Thermo Fisher Scientific TCP-1 beta Polyclonal Antibody
Rabbit polyclonal antibody against human TCP-1 beta. Validated for Western blot with dilution 1:500–1:3,000. Recognizes multiple species including mouse, rat, and zebrafish. Supplied as liquid, 0.74 mg/mL. Store at 4°C short term or -20°C long term.
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- PA529439
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested dilution: 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fragment corresponding to a region within amino acids 45–336 of Human TCP-1 beta |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.74 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2546915 |
Product Specific Information
- Recommended positive control: A549
- Predicted reactivity: Mouse (97%), Rat (99%), Zebrafish (89%), Xenopus laevis (89%), Pig (98%), Rabbit (99%), Chicken (95%), Rhesus Monkey (100%), Chimpanzee (100%), Bovine (98%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
TCP-1 beta is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC).
The CCT complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner.
The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of the TCP-1 beta gene have been observed but not thoroughly characterized.
A disease associated with TCP-1 beta protein dysfunction includes epididymo-orchitis.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information go to www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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