Thermo Fisher Scientific IL-4 Monoclonal Antibody (A155B15C6), Biotin

Applications

• ELISA (ELISA)
  • Tested Dilution: Assay-dependent
  • View 2 publications

Product Specifications

Product Specific Information

This product is recommended as a detection antibody in Sandwich ELISA applications.
This clone can also be referred to as clone number A155B 15C6 1H8.

Target Information

Interleukin-4 (IL-4) is a pleiotropic, immune-modulatory cytokine produced by activated T cells, and serves as a ligand for interleukin 4 receptor. IL-4 has been found to have the broadest range of actions. The interleukin 4 receptor also binds to IL13, which may contribute to many overlapping functions of this cytokine and IL13. STAT6, a signal transducer and activator of transcription, plays an important role in mediating the immune regulatory signal of IL-4.

The IL-4 gene, IL-3, IL-5, IL-13, and CSF2 form a cytokine gene cluster on chromosome 5q. IL-4 is located in close proximity to IL13, and IL-4, IL13, and IL5 are coordinated by several long-range regulatory elements over a 120 kb range on the chromosome. IL-4 delta 2 is a known splice variant of IL-4.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.