Thermo Fisher Scientific APBB1 Monoclonal Antibody (OTI1G1), TrueMAB
인간 APBB1 단백질을 인식하는 마우스 단클론 항체로 Western blot에 적합합니다. TrueMAB 포맷으로 높은 특이성과 재현성을 제공합니다. PBS/BSA/glycerol 완충액에 보관되며, -20°C에서 안정적입니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA811192
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500–1:2,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1G1 |
| Immunogen | Full length human recombinant protein of human APBB1 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the Fe65 protein family and acts as an adaptor protein localized in the nucleus. It interacts with the Alzheimer’s disease amyloid precursor protein (APP), transcription factor CP2/LSF/LBP1, and the low-density lipoprotein receptor-related protein. APP functions as a cytosolic anchoring site that can prevent the gene product’s nuclear translocation. This encoded protein may play an important role in the pathogenesis of Alzheimer’s disease and is thought to regulate transcription. It has also been observed to block cell cycle progression by downregulating thymidylate synthase expression. Multiple alternatively spliced transcript variants have been described for this gene, though some full-length sequences remain unknown.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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