Thermo Fisher Scientific Phospho-EIF4EBP1 (Ser101) Polyclonal Antibody
Phospho-EIF4EBP1 (Ser101) 폴리클로날 항체로, Western blot, IHC, ICC, ELISA 등에 사용 가능. Mouse 시료에 반응하며 Rabbit에서 유래. Protein A로 정제된 액상 형태로, 안정적인 저장 및 재현성 높은 결과 제공.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry / Immunofluorescence (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic phosphopeptide derived from mouse 4EBP1 around the phosphorylation site of Ser101 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the translation repressor protein family. The protein interacts directly with eukaryotic translation initiation factor 4E (eIF4E), a key component in recruiting 40S ribosomal subunits to the 5′ end of mRNAs. Interaction with eIF4E inhibits complex assembly and represses translation. Phosphorylation in response to signals such as UV irradiation and insulin signaling causes dissociation from eIF4E and activation of mRNA translation.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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