Thermo Fisher Scientific CD105 Monoclonal Antibody (MJ7/18), Biotin
Mouse CD105(Endoglin)을 표적하는 Biotin 결합 단일클론 항체로, FACS·IHC·IP·WB에 사용 가능. Rat IgG2a 기반으로 높은 특이성과 재현성을 제공. 단기 4℃, 장기 -20℃ 보관 권장. 연구용으로만 사용.
- 카탈로그번호
- MA517944
- 판매단위
- pk
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Thermo Fisher Scientific CD105 Monoclonal Antibody (MJ7/18), Biotin
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | Assay-dependent |
| Immunohistochemistry (IHC) | Assay-dependent |
| Flow Cytometry (Flow) | 0.5 µg / 1×10⁶ cells |
| Immunoprecipitation (IP) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse |
| Host / Isotype | Rat / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | MJ7/18 |
| Immunogen | Rat monoclonal antibody raised against inflamed mouse skin |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 4–5 mg/mL BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2539328 |
Additional Formats
Product Specific Information
MA5-17944 targets CD105/Endoglin in FACS, IHC, IP, and WB applications and shows reactivity with Mouse samples.
The immunogen is a rat monoclonal antibody raised against inflamed mouse skin.
Target Information
CD105 (Endoglin) is a Type I transmembrane protein highly expressed on human vascular endothelial cells. It forms an O- and N-glycosylated homodimer. Upregulation of endoglin expression has been observed in tumor vasculature and proliferating cells, indicating its role as a proliferation-associated endothelial marker. CD105 binds TGF beta 1 and 3 with high affinity but not TGF beta 2.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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