Thermo Fisher Scientific ALKBH3 Polyclonal Antibody
Thermo Fisher Scientific의 ALKBH3 Polyclonal Antibody는 인간 및 랫트 반응성을 가진 rabbit IgG 폴리클로날 항체입니다. Western blot에 적합하며, DNA 복구 관련 단백질인 ALKBH3를 검출합니다. 고순도 항원 친화 크로마토그래피로 정제되어 안정적인 신호를 제공합니다.
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Thermo Fisher Scientific ALKBH3 Polyclonal Antibody
Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein encompassing a sequence within the center region of human DEPC-1 (exact sequence proprietary) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2.06 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7, with 20% glycerol |
| Contains | 0.025% ProClin 300 |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2735445 |
Product Specific Information
- Positive Control: Rat stomach
- Predicted Reactivity: Human (100%), Rhesus Monkey (97%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Dioxygenase that repairs alkylated DNA containing 1-methyladenine (1meA) and 3-methylcytosine (3meC) by oxidative demethylation. Has a strong preference for single-stranded DNA. Able to process alkylated 3mC within double-stranded regions via its interaction with ASCC3, which promotes DNA unwinding to generate single-stranded substrate needed for ALKBH3. May also act on RNA. Requires molecular oxygen, alpha-ketoglutarate, and iron.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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