Thermo Fisher Scientific AP2 beta Polyclonal Antibody

Applications

• Immunohistochemistry (Paraffin) (IHC (P))
  Tested Dilution: 1:200–1:500

Product Specifications

Product Specific Information

Immunogen sequence:
QRQRQEVGSE AGSLLPQPRA ALPQLSGLDP RRDYHSVRRP DVLLHSAHHG LDAGMG

Target Information

This gene encodes a member of the AP-2 family of transcription factors. AP-2 proteins form homo- or hetero-dimers with other AP-2 family members and bind specific DNA sequences. They are thought to stimulate cell proliferation and suppress terminal differentiation of specific cell types during embryonic development. Specific AP-2 family members differ in their expression patterns and binding affinity for different promoters. This protein functions as both a transcriptional activator and repressor. Mutations in this gene result in autosomal dominant Char syndrome, suggesting that this gene functions in the differentiation of neural crest cell derivatives.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.

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