Thermo Fisher Scientific SEMA6D Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 SEMA6D 폴리클로날 항체로, IHC, ICC/IF, ELISA 등 다양한 응용에 적합. Rabbit IgG로 제작되었으며, Protein A로 정제된 액상 형태. -20°C에서 보관하며 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human SEMA6D, amino acids 801–900 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 1% BSA, 50% glycerol |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Semaphorins are a large family including both secreted and membrane-associated proteins, many of which function as inhibitors or chemorepellents in axon pathfinding, fasciculation, branching, and target selection. All semaphorins possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins, and integrins) in the N-terminal extracellular portion. Additional sequence motifs C-terminal to the semaphorin domain allow classification into distinct subfamilies.
Transmembrane semaphorins, like secreted ones, can act as repulsive axon guidance cues. SEMA6D is a class 6 vertebrate transmembrane semaphorin that undergoes alternative splicing. Six transcript variants have been identified, and expression of the distinct isoforms is regulated in a tissue- and development-dependent manner.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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