Thermo Fisher Scientific GSDMB Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human GSDMB. Recombinant protein control fragment (Product #RP-93176). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:GSDMB,uniProtId:Q8TAX9-4,ncbiNodeId:9606,antigenRange:18-105,antigenLength:416,antigenImageFileName:PA5-54929_GSDMB_Q8TAX9-4_Rabbit.svg,antigenImageFileNamePDP:PA5-54929_GSDMB_Q8TAX9-4_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2642236

Product Specific Information

Immunogen sequence: AGGDMIAVRS LVDADRFRCF HLVGEKRTFF GCRHYTTGLT LMDILDTDGD KWLDELDSGL QGQKAEFQIL DNVDSTGELI VRLPKEIT

Highest antigen sequence identity to the following orthologs: Mouse - 34%, Rat - 33%.

Target Information

This gene encodes a member of the gasdermin-domain containing protein family. Other gasdermin-family genes are implicated in the regulation of apoptosis in epithelial cells, and are linked to cancer. Multiple transcript variants encoding different isoforms have been found for this gene. Additional variants have been described, but they are candidates for nonsense-mediated mRNA decay (NMD) and are unlikely to be protein-coding.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.