Thermo Fisher Scientific SLUG Polyclonal Antibody
Thermo Fisher Scientific의 SLUG Polyclonal Antibody는 인간 SNAIL2(82-110 aa)를 면역원으로 제작된 Rabbit IgG 폴리클로날 항체입니다. WB, IHC, ICC 등 다양한 응용에 적합하며, 액상 형태로 제공됩니다. 연구용으로만 사용되며 4°C 단기, -20°C 장기 보관 가능합니다.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:2,000 | View 1 publication |
| Immunohistochemistry (IHC) | - | View 2 publications |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 | View publications |
| Immunocytochemistry (ICC/IF) | 1:100 | View publications |
Product Specifications
| Specification | Description |
|---|---|
| Published species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Amino acids 82–110 of human SNAIL2 (SNAI2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2718869 |
Target Information
Slug, a member of the Snail family of C2H2-type zinc finger transcription factors, is involved in epithelial-mesenchymal transitions and neural tube formation during vertebrate embryogenesis. Slug transcription can be induced by growth factors such as FGF, BMP, and TGF-beta. It binds E-box regions of promoters and represses transcription of genes like E-cadherin and Claudin-1. Expression of Slug in breast, esophageal, and colorectal carcinomas correlates with poor prognosis. Additionally, Slug protects hemopoietic progenitor cells from radiation-induced apoptosis by repressing p53-mediated transcription of Puma.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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