Thermo Fisher Scientific MAST2 Polyclonal Antibody
Thermo Fisher Scientific의 MAST2 폴리클로날 항체는 인간 및 생쥐 시료에서 MAST2 단백질을 검출하기 위한 고품질 항체입니다. Western blot과 면역세포화학(ICC/IF)에 적합하며, 고순도 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100–1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human MAST2 (Accession Q6P0Q8), corresponding to amino acid residues K1183–R1233 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853814 |
Product Specific Information
Antibody detects endogenous levels of total MAST2.
Target Information
Syntrophin is an adapter protein that binds signaling molecules to the dystrophin-associated protein complex, connecting the extracellular matrix to the intracellular cytoskeleton for postsynaptic structure maintenance in the neuromuscular junction and CNS.
Microtubule-associated serine/threonine-protein kinase 2 (MAST205) is a testis-specific cytoplasmic protein involved in spermatid maturation. It links the dystrophin/utrophin network with microtubule filaments via Syntrophin and regulates IL-12 synthesis in macrophages by forming a complex with TRAF6, inhibiting TRAF6 NF-κB activation.
Two isoforms exist due to alternative splicing: isoform 1 (full length) and isoform 2 (lacking residues 327–396 and 1091–1113). Phosphorylation at the N-terminus enables ubiquitination, leading to proteasome-mediated degradation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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