Thermo Fisher Scientific PIK3R4 Polyclonal Antibody
Human PIK3R4 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC(P) 및 ICC/IF에 사용 가능. 항원 친화 크로마토그래피로 정제되었으며, PBS(glycerol 포함) 용액 형태. 세포 내 자가포식 및 엔도사이토시스 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human PIK3R4. Recombinant protein control fragment (Product # RP-102691) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2790459 |
Product Specific Information
Immunogen sequence:
QLLAYRNGHF FPEQVLNKIE DHSIRELVTQ MIHREPDKRL EAEDYLKQQR GNAFPEIFYT FLQPYMAQFA KETFLSADER ILVIRKDLG
Target Information
Regulatory subunit of the PI3K complex that mediates formation of phosphatidylinositol 3-phosphate.
Different complex forms are believed to play a role in multiple membrane trafficking pathways:
- PI3KC3-C1: Involved in initiation of autophagosomes
- PI3KC3-C2: Involved in maturation of autophagosomes and endocytosis
Involved in regulation of degradative endocytic trafficking and cytokinesis, probably in the context of PI3KC3-C2 (PubMed:20643123). [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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