Thermo Fisher Scientific TNFSF13 Monoclonal Antibody (G3)
인간 TNFSF13(APRIL)을 인식하는 Mouse monoclonal antibody(G3). Western blot과 ELISA에 적합하며, Affinity chromatography로 정제된 액상 항체. PBS(pH 7.4) buffer에 보존되며, 보존제 무첨가. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| ELISA | 0.1 ng/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | G3 |
| Immunogen | TNFSF13 (AAH08042, 1–247 a.a.) full-length recombinant protein with GST tag (GST tag MW: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Protein sequence:
MPASSPFLLA PKGPPGNMGG PVREPALSVA LWLSWGAALG AVACAMALLT QQTELQSLRR EVSRLQGTGG
PSQNGEGYPW QSLPEQSSDA LEAWESGERS RKRRAVLTQK QKKQHSVLHL VPINATSKDD SDVTEVMWQP
ALRRGRGLQA QGYGVRIQDA GVYLLYSQVL FQDVTFTMGQ VVSREGQGRQ ETLFRCIRSM PSHPDRAYNS
CYSAGVFHLH QGDILSVIIP RARAKLNLSP HGTFLGLTarget Information
Members of the TNF superfamily regulate immune responses and induce apoptosis. A novel member, APRIL (A Proliferation-Inducing Ligand), also known as TALL2 or TRDL1a, has been identified in human and mouse. Two receptors for APRIL, TACI and BCMA, mediate its biological effects. APRIL promotes B and T cell proliferation, triggers humoral immune responses, activates NF-κB, and induces cell death. APRIL and its related ligand BlyS, along with their receptors BCMA and TACI, are implicated in autoimmune diseases and cancer.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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