Thermo Fisher Scientific UBL4B Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:100-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Full length fusion protein of human UBL4B if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:UBL4B,uniProtId:Q8N7F7-1,ncbiNodeId:9606,antigenRange:1-174,antigenLength:174,antigenImageFileName:PA5-51149_UBL4B_Q8N7F7-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51149_UBL4B_Q8N7F7-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.4 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.4, with 40% glycerol

Contains

0.05% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2636597

Product Specific Information

The antibody detects endogenous levels of total UBL4B protein.

Target Information

Ubiquitin is a 77 amino acid protein that targets proteins for degradation by the 26S proteasome. Ubiquitin-like proteins are not directly involved in protein degradation, but appear to have many mechanistic similarities with the ubiquitin pathway. UBL4B (Ubiquitin-like protein 4B) is a 174 amino acid cytoplasmic protein that contains a ubiquitin-like domain. UBL4B likely arose by retroposition during mammalian evolution from UBL4A, an X-linked intron-bearing housekeeping gene. While UBL4A is highly conserved, UBL4B has undergone rapid evolution and may have evolved new functions. Expression of UBL4B is restricted to post-meiotic germ cells in testis and ovarian tissue, where it likely functions in post-translational protein modification.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.