Thermo Fisher Scientific GPR20 Polyclonal Antibody
GPR20 단백질을 인식하는 Rabbit Polyclonal 항체로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat에 반응하며, Protein A 정제 및 고순도 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:50–1:200 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human G protein coupled receptor 20 (amino acids 51–150) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors or 7TM receptors, are a large superfamily of proteins that mediate various stimulus-response pathways. These receptors translate extracellular signals into intracellular responses through G protein activation and are involved in sensing hormones and neurotransmitters.
GPR20 is a 358-amino-acid membrane protein that constitutively activates G(i) proteins without ligand stimulation. It may play a role in regulating intracellular cAMP levels and mitogenic signaling. GPR20 is expressed in the liver and specific brain regions such as the putamen, caudate, and thalamus, but not in the hypothalamus, pons, or frontal cortex.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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