Thermo Fisher Scientific NMDAR2A Polyclonal Antibody
NMDAR2A 단백질을 인식하는 Thermo Fisher Scientific의 폴리클로날 항체. Western blot, IHC, ICC, ELISA, IP 등 다양한 응용 가능. 사람, 마우스, 랫트 반응성. 동결건조 형태로 보관 용이하며 장기 안정성 우수.
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Applications and Tested Dilutions
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:100–1:500 | 17 publications |
| Immunohistochemistry (IHC) | – | 2 publications |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:500–1:5,000 | – |
| Immunocytochemistry (ICC/IF) | – | 3 publications |
| ELISA | Assay-dependent | – |
| Immunoprecipitation (IP) | 3 µL | 1 publication |
| Miscellaneous PubMed (Misc) | – | 1 publication |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Fusion protein containing amino acid residues 1253–1391 of the C-terminal region of rat brain subunit 2A |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Purification | IgG fraction |
| Storage Buffer | PBS |
| Contains | No preservative |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2536209 |
Product Specific Information
This antibody recognizes the 180 kDa 2A subunit from rat, mouse, and human, and does not cross-react with the 2B or 2C subunits.
Storage and Reconstitution:
When stored at -20ºC or below, the lyophilized antibody retains full activity for over one year.
Reconstitute using 50 µL PBS (pH 7.4) to yield a 0.2 mg/mL solution.
If storing at 0–4ºC, add sodium azide to a final concentration of 2 mM.
For longer storage, divide into aliquots and freeze at -20ºC, avoiding freeze/thaw cycles.
Target Information
N-methyl-D-aspartate (NMDA) receptors are ionotropic glutamate-gated ion channels involved in long-term potentiation, an activity-dependent increase in synaptic transmission efficiency underlying certain types of memory and learning.
NMDA receptor channels are heteromers composed of the key receptor subunit NMDAR1 (GRIN1) and one or more of the four NMDAR2 subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C), and NMDAR2D (GRIN2D).
Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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