Thermo Fisher Scientific HYAL1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:500

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 136-435 of human HYAL1 (NP_1493492) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:HYAL1,uniProtId:Q12794-1,ncbiNodeId:9606,antigenRange:136-435,antigenLength:435,antigenImageFileName:PA5-93104_HYAL1_Q12794-1_Rabbit.svg,antigenImageFileNamePDP:PA5-93104_HYAL1_Q12794-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1.13 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2806626

Product Specific Information

Immunogen sequence: RWAFNWDTKD IYRQRSRALV QAQHPDWPAP QVEAVAQDQF QGAARAWMAG TLQLGRALRP RGLWGFYGFP DCYNYDFLSP NYTGQCPSGI RAQNDQLGWL WGQSRALYPS IYMPAVLEGT GKSQMYVQHR VAEAFRVAVA AGDPNLPVLP YVQIFYDTTN HFLPLDELEH SLGESAAQGA AGVVLWVSWE NTRTKESCQA IKEYMDTTLG PFILNVTSGA LLCSQALCSG HGRCVRRTSH PKALLLLNPA SFSIQLTPGG GPLSLRGALS LEDQAQMAVE FKCRCYPGWQ APWCERKSMW; Positive Samples: Mouse liver, Mouse lung; Cellular Location: Lysosome

Target Information

This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.