Thermo Fisher Scientific HYAL1 Polyclonal Antibody
HYAL1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, ELISA 등에 사용 가능. 인간, 마우스, 랫트 반응성. 고순도 Affinity Chromatography 정제, 액상 형태, 연구용으로 적합.
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Thermo Fisher Scientific HYAL1 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:100–1:500 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein corresponding to amino acids 136–435 of human HYAL1 (NP_1493492) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.13 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2806626 |
Product Specific Information
Immunogen sequence:
RWAFNWDTKD IYRQRSRALV QAQHPDWPAP QVEAVAQDQF QGAARAWMAG TLQLGRALRP RGLWGFYGFP DCYNYDFLSP NYTGQCPSGI RAQNDQLGWL WGQSRALYPS IYMPAVLEGT GKSQMYVQHR VAEAFRVAVA AGDPNLPVLP YVQIFYDTTN HFLPLDELEH SLGESAAQGA AGVVLWVSWE NTRTKESCQA IKEYMDTTLG PFILNVTSGA LLCSQALCSG HGRCVRRTSH PKALLLLNPA SFSIQLTPGG GPLSLRGALS LEDQAQMAVE FKCRCYPGWQ APWCERKSMW
Positive Samples: Mouse liver, Mouse lung
Cellular Location: Lysosome
Target Information
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, a major glycosaminoglycan of the extracellular matrix. Hyaluronan is involved in cell proliferation, migration, and differentiation.
The enzyme is active at acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX (hyaluronidase deficiency). The gene is located in chromosome 3p21.3, a region associated with tumor suppression. Multiple transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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