Thermo Fisher Scientific HLA-DR/DP/DQ Monoclonal Antibody (Bu26), FITC
인간 HLA-DR/DP/DQ 항원을 인식하는 단클론 항체로, FITC 형광 표지되어 유세포분석(Flow Cytometry)에 적합합니다. Protein G로 정제되었으며, PBS와 1% BSA, 0.09% sodium azide로 보존됩니다. 항원제시세포 분석 및 면역반응 연구에 활용됩니다.
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Applications
- Flow Cytometry (Flow)
Tested Dilution: Neat–1:10
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | Bu26 |
| Immunogen | The details of the immunogen for this antibody are not currently available. |
| Conjugate | FITC |
| Excitation / Emission Max | 498 / 517 nm |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS with 1% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C (short term). For long term storage, store at −20°C, avoiding freeze/thaw cycles. Store in the dark. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2538097 |
Additional Formats
Product Specific Information
For FACS analysis, use 10 µL of the suggested working dilution to label 1×10^6 cells in 100 µL.
Target Information
MHC class II molecules are transmembrane glycoproteins composed of an alpha chain (36 kDa) and a beta chain (27 kDa). They are expressed primarily on antigen-presenting cells such as B lymphocytes, monocytes, macrophages, thymic epithelial cells, and activated T lymphocytes.
Three loci—DR, DQ, and DP—encode the major expressed products of the human class II region.
Human MHC class II molecules bind intracellularly processed peptides and present them to T-helper cells, playing a critical role in initiating the immune response.
HLA and MHC antibodies are essential in immunopeptidomics, enabling identification and characterization of neoantigens through high-performance liquid chromatography coupled to tandem mass spectrometry.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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