Thermo Fisher Scientific CYP2B6 Monoclonal Antibody (OTI3D5), TrueMAB
CYP2B6 단백질을 인식하는 마우스 단클론 항체로, WB, IHC, ICC, Flow Cytometry에 사용 가능. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공되며, 인체, 마우스, 랫트, 개 시료에 반응. 연구용으로 약물 대사 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host/Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3D5 |
| Immunogen | Full-length human recombinant protein of human CYP2B6 produced in HEK293T cells |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | −20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL of distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
CYP2B6 encodes a cytochrome P450 enzyme involved in drug metabolism and lipid synthesis.
This enzyme localizes to the endoplasmic reticulum and is induced by phenobarbital.
It metabolizes xenobiotics such as cyclophosphamide and ifosphamide.
CYP2B6 and its pseudogene CYP2B7 are located within a large CYP2 gene cluster on chromosome 19q.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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