Thermo Fisher Scientific Human AIFM3 Synthetic Peptide
인간 AIFM3 단백질의 중심부 16개 아미노산 서열을 기반으로 한 합성 펩타이드. AIFM3 관련 항체의 블로킹 실험에 사용 가능. 정제된 액상 형태로 제공되며 PBS 버퍼에 0.1% BSA 및 0.02% sodium azide 포함. 연구용으로만 사용.
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Thermo Fisher Scientific Human AIFM3 Synthetic Peptide
Applications
- Control (Ctrl): Assay-dependent
- Blocking Assay (BLOCK): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to 16 amino acids near the center of human AIFM3.
PEP-0623 can be used as a blocking peptide with polyclonal antibody PA5-20503.
Target Information
Apoptosis, or programmed cell death, is critical for development, tissue turnover, and tumor formation. A protein homologous to apoptosis-inducing factor (AIF), designated AIFL (also known as AIFM3), has been cloned.
AIFM3 is ubiquitously expressed and localized to the inner mitochondrial membrane. Unlike AIF, AIFM3 does not translocate to the nucleus upon apoptosis induction. Overexpression of AIFM3 induces cytochrome c release, caspase 3 cleavage, and apoptosis through caspase activation. Multiple isoforms of AIFM3 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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