Thermo Fisher Scientific HSD17B4 Monoclonal Antibody (OTI1F3)
HSD17B4 단백질을 인식하는 마우스 단클론 항체로, Western blot, IHC(P), ICC/IF에 사용 가능. 인간 시료 반응성. 액상 형태, 1 mg/mL 농도, PBS 기반 보존액 포함. 연구용으로만 사용 가능.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:4,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI1F3 |
| Immunogen | Full length human recombinant protein of HSD17B4 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2724480 |
Target Information
Peroxisomal multifunctional enzyme type 2 is a protein encoded by the HSD17B4 gene in humans. This bifunctional enzyme participates in the peroxisomal beta-oxidation pathway of fatty acids and catalyzes the formation of 3-ketoacyl-CoA intermediates from both straight-chain and 2-methyl-branched-chain fatty acids.
Defects in this gene that impair peroxisomal fatty acid beta-oxidation activity cause D-bifunctional protein deficiency (DBPD).
A pseudogene is located on chromosome 8, and several alternatively spliced transcript variants encoding distinct isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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