Thermo Fisher Scientific Human TCTN1 Synthetic Peptide
인간 TCTN1 단백질의 아미노 말단 15개 아미노산 서열에 해당하는 합성 펩타이드입니다. 항체 PA5-20983과 함께 블로킹 펩타이드로 사용 가능합니다. 순도 높은 액상 형태로 제공되며, PBS 버퍼에 0.1% BSA 및 0.02% sodium azide가 포함되어 있습니다. 연구용으로만 사용됩니다.
- 카탈로그번호
- PEP1097
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
Product Specific Information
This peptide corresponds to 15 amino acids near the amino terminus of human TCTN1.
PEP-1097 can be used as a blocking peptide with polyclonal antibody PA5-20983.
Target Information
TCTN1 is the founding member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate Hedgehog (Hh)-mediated patterning of the neural tube. During embryonic development, TCTN1 is expressed in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later developmental stages, TCTN1 may also act as a repressor on the Hh pathway in the anterior and posterior neural tube.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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