Thermo Fisher Scientific NAPEPLD Monoclonal Antibody (OTI5F3), TrueMAB
인간 NAPEPLD 단백질을 인식하는 Mouse IgG2a 단일클론 항체로 WB, IHC, Flow Cytometry에 적합. 고순도 친화 크로마토그래피로 정제되었으며, PBS/BSA/glycerol buffer에 보존. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI5F3 |
| Immunogen | Full length human recombinant protein of human NAPEPLD produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.71 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
N-Acylphosphatidylethanolamine (NAPE)-hydrolyzing phospholipase D (NAPE-PLD) is a membrane-bound enzyme that releases the endocannabinoid anandamide and other bioactive N-acylethanolamines from their corresponding NAPEs in animal tissues.
NAPE-PLD is expressed by specific populations of neurons in the brain and targeted to axonal processes.
Studies suggest that NAEs generated by NAPE-PLD in axons may act as anterograde synaptic signaling molecules that regulate postsynaptic neuronal activity.
Additionally, NAPE-PLD catalyzes the hydrolysis of NAPE to generate OEA (oleoylethanolamide), a natural lipid amide that inhibits food intake in rodents.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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