Thermo Fisher Scientific IL6 Monoclonal Antibody (2D12)
인간 IL-6 단백질을 표적으로 하는 마우스 단클론 항체로, Western blot 및 ELISA에 적합합니다. 고순도 친화 크로마토그래피 정제, PBS 버퍼에 보존제 없이 제공되며 연구용으로만 사용 가능합니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1–5 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 2D12 |
| Immunogen | IL6 (NP_000591, 29 a.a.–212 a.a.) full-length recombinant protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
SPVPPGEDSK DVAAPHRQPL TSSERIDKQI RYILDGISAL RKETCNKSNM CESSKEALAE NNLNLPKMAE KDGCFQSGFN EETCLVKIIT GLLEFEVYLE YLQNRFESSE EQARAVQMST KVLIQFLQKK AKNLDAITTP DPTTNASLLT KLQAQNQWLQ DMTTHLILRS FKEFLQSSLR ALRQM
Target Information
IL-6 is a cytokine involved in inflammation and B cell maturation. The protein encoded by IL6 acts as an endogenous pyrogen, inducing fever in autoimmune diseases or infections. It is primarily expressed at sites of acute and chronic inflammation, secreted into serum, and triggers a transcriptional inflammatory response via the interleukin 6 receptor alpha.
IL6 function is implicated in various inflammation-associated diseases, including diabetes mellitus susceptibility and systemic juvenile rheumatoid arthritis. Elevated IL-6 levels are observed in viral infections such as COVID-19.
Diseases associated with IL6 include Kaposi Sarcoma and Systemic Juvenile Rheumatoid Arthritis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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