Thermo Fisher Scientific TXNRD1 Polyclonal Antibody
TXNRD1 단백질을 인식하는 Rabbit Polyclonal 항체로, Western blot, IHC, ICC, ELISA 등 다양한 응용에 사용 가능. Human, Mouse, Rat 반응성. 고순도 Protein A 정제 및 안정한 보관용 buffer 구성. 연구용으로 산화 스트레스 관련 연구에 적합.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:200 |
| Immunohistochemistry (Paraffin) (IHC-P) | 1:400 |
| Immunohistochemistry (Frozen) (IHC-F) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH-conjugated synthetic peptide derived from human TXNRD1 (amino acids 451–550) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | –20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a member of the pyridine nucleotide oxidoreductase family. The encoded protein reduces thioredoxins and other substrates, playing a critical role in selenium metabolism and protection against oxidative stress. The enzyme functions as a homodimer using FAD as a cofactor. Each subunit includes a selenocysteine (Sec) residue essential for catalytic activity, encoded by the UGA codon, which typically signals translation termination. The 3′ UTR contains a SECIS element that allows UGA to be recognized as a Sec codon. Alternative splicing produces several transcript variants encoding the same or different isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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