
Thermo Fisher Scientific FEN1 Monoclonal Antibody (OTI3A8), TrueMAB
FEN1 단백질을 인식하는 Mouse IgG1 단일클론 항체로, Western blot 및 IHC(P) 실험에 적합. 인간 FEN1(aa117–380) 재조합 단백질을 면역원으로 제작. 고순도 친화 크로마토그래피 정제, PBS/BSA/glycerol 버퍼에 보존. 연구용으로만 사용 가능.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3A8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 117–380 of human FEN1 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
FEN-1 (Flap Endonuclease and Five prime Exonuclease) is a 42 kDa protein functioning as an endonuclease that cleaves branched DNA structures containing single-stranded 5′ flaps, or as an exonuclease on DNA nicks and gaps. Its endonuclease and exonuclease activities are stimulated by association with proliferating cell nuclear antigen (PCNA) in the nucleus. FEN-1 plays critical roles in DNA replication and repair and is required in cell-free DNA replication systems.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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