Thermo Fisher Scientific HSD17B8 Monoclonal Antibody (OTI6H2), TrueMAB
HSD17B8 단백질을 인식하는 Mouse IgG1 단클론 항체로 Western blot 및 IHC(P) 검증 완료. 인간 및 개 반응성. 고순도 친화 크로마토그래피 정제, 동결건조 형태로 제공. 연구용으로 에스트라디올 관련 대사 연구에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:150
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6H2 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 57–261 of human HSD17B8 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to achieve a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments, perform an additional desalting step using Zeba Spin Desalting Columns (7K MWCO, 0.5 mL, Product #89882).
Target Information
NAD-dependent 17-beta-hydroxysteroid dehydrogenase with highest activity towards estradiol and very low activity towards testosterone.
The heterotetramer with CBR4 exhibits NADH-dependent 3-ketoacyl-acyl carrier protein reductase activity and may play a role in mitochondrial fatty acid biosynthesis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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