Thermo Fisher Scientific CTRP1 Polyclonal Antibody
Thermo Fisher Scientific의 CTRP1 Polyclonal Antibody는 인간, 마우스, 랫트 시료에 반응하는 Rabbit IgG 기반 항체입니다. IHC, ICC/IF, ELISA 등 다양한 응용에 적합하며, 고순도 Protein A 정제 및 안정적인 보관용 버퍼를 제공합니다. 연구용으로만 사용됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human CTRP1, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Adipose tissue plays a major role in regulating physiological and pathological processes such as metabolism and immunity by producing and secreting various bioactive molecules called adipokines.
The adiponectin/ACRP30 family and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1–7, are highly conserved adipokines.
Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, CTRPs are expressed in a wide range of tissues and act mainly on liver and muscle to control glucose and lipid metabolism.
Structural analysis of adiponectin revealed an evolutionary link between TNF and C1q-containing proteins, suggesting a common ancestral innate immunity gene.
In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are significantly elevated in adipose tissue compared to normal mice.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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