Thermo Fisher Scientific RPS6KA2 Monoclonal Antibody (OTI3C8), TrueMAB
RPS6KA2 단백질을 인식하는 단클론 항체로, Western blot에 적합합니다. Human, Mouse, Rat 시료에 반응하며, IgG1 아이소타입입니다. 동결건조 형태로 제공되며, PBS 완충액에 8% 트레할로스를 포함합니다. 연구용으로만 사용 가능합니다.
- 판매단위
- pk
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Applications
- Western Blot (WB): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3C8 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 1–51 of human RPS6KA2 produced in E. coli |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.3, with 8% trehalose |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
For reconstitution, add 100 µL distilled water to obtain a final antibody concentration of approximately 1 mg/mL.
For conjugation experiments using this carrier-free antibody, perform an additional desalting step (e.g., Zeba Spin Desalting Columns, 7K MWCO, 0.5 mL, Product #89882).
Target Information
RPS6KA2 (RSK3) serine/threonine kinase is a member of the ribosomal S6 kinase (RSK) family. It functions as a signal-transducing intermediate in the cellular response to several growth factors. RPS6KA2 is expressed in many tissues, with higher levels in lung and skeletal muscle. The p90 ribosomal S6 kinases (RSK1–4) are downstream members of the ERK/MAPK cascade. Loss of RSK2 activity in humans leads to Coffin-Lowry syndrome, characterized by mental retardation and growth deficits, and may affect tonic regulation of G-protein coupled signaling.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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