Thermo Fisher Scientific CAT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:100-1:500

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 380-626 of human CRAT (NP_0007463) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CAT1,uniProtId:P43155-1,ncbiNodeId:9606,antigenRange:380-626,antigenLength:626,antigenImageFileName:PA5-109589_CAT1_P43155-1_Rabbit.svg,antigenImageFileNamePDP:PA5-109589_CAT1_P43155-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.69 mg/mL

Purification

Affinity Chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol

Contains

0.05% ProClin 300

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Wet ice

RRID

AB_2855000

Product Specific Information

Immunogen sequence: KLRFNITPEI KSDIEKAKQN LSIMIQDLDI TVMVFHHFGK DFPKSEKLSP DAFIQMALQL AYYRIYGQAC ATYESASLRM FHLGRTDTIR SASMDSLTFV KAMDDSSVTE HQKVELLRKA VQAHRGYTDR AIRGEAFDRH LLGLKLQAIE DLVSMPDIFM DTSYAIAMHF HLSTSQVPAK TDCVMFFGPV VPDGYGVCYN PMEAHINFSL SAYNSCAETN AARLAHYLEK ALLDMRALLQ SHPRAKL

Target Information

Carnitine acetyltransferase (CRAT) is a key enzyme in the metabolic pathway in mitochondria, peroxisomes and endoplasmic reticulum. CRAT catalyzes the reversible transfer of acyl groups from an acyl-CoA thioester to carnitine and regulates the ratio of acylCoA/CoA in the subcellular compartments. Different subcellular localizations of the CRAT mRNAs are thought to result from alternative splicing of the CRAT gene suggested by the divergent sequences in the 5` region of peroxisomal and mitochondrial CRAT cDNAs and the location of an intron where the sequences diverge. The alternatively splicing of this gene results in three distinct isoforms, one of which contains an N-terminial mitochondrial transit peptide, and has been shown to be located in mitochondria.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.