Thermo Fisher Scientific Ku80 Polyclonal Antibody
Hamster, Human, Mouse, Rat에서 반응하는 Ku80 단백질에 대한 Rabbit Polyclonal 항체. Western blot 검증 완료. 합성 펩타이드(aa 419-440) 면역원 사용. Protein A로 정제된 액상 형태로, PBS(pH 7.4)에 보존제 없이 제공. -20°C 보관 권장.
- 카탈로그번호
- 12527-100UG
- 판매단위
- pk
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Applications
Western Blot (WB)
- Tested Dilution: 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Hamster, Human, Mouse, Rat |
| Host/Isotype | Rabbit |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to amino acids 419-440 (LVYVQLPFMEDLRQYMFSSLKN) of Ku80 conjugated to KLH at the N-terminus |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5–1.0 mg/mL |
| Purification | Protein A |
| Storage buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is the 80-kilodalton subunit of the Ku heterodimer protein, also known as ATP-dependent DNA helicase II or DNA repair protein XRCC5. Ku functions as the DNA-binding component of the DNA-dependent protein kinase and acts with the DNA ligase IV–XRCC4 complex in repairing DNA double-strand breaks via non-homologous end joining and in completing V(D)J recombination events. This gene complements Chinese hamster xrs-6, a mutant defective in DNA double-strand break repair and V(D)J recombination. A rare microsatellite polymorphism in this gene is associated with cancer in patients with varying radiosensitivity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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