Thermo Fisher Scientific Phospho-CREB (Ser133) Recombinant Rabbit Monoclonal Antibody (CREBS133-4D11), APC
Phospho-CREB (Ser133) 인산화 단백질을 검출하는 토끼 단클론 항체. 인체 및 마우스 시료에 반응하며, APC 형광 표지로 유세포분석에 최적. 재조합 항체로 로트 간 일관성과 높은 특이도 제공. 연구용으로만 사용 가능.
✨AI 추천 연관 상품
AI가 분석한 이 상품과 연관된 추천 상품들을 확인해보세요
연관 상품을 찾고 있습니다...
Applications
- Flow Cytometry (Flow): 5 µL / 1×10⁶ cells
- View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | CREBS133-4D11 |
| Immunogen | A synthetic phospho-peptide corresponding to residues surrounding Ser133 of human phospho CREB |
| Conjugate | APC |
| Excitation / Emission Max | 651 / 660 nm |
| Form | Liquid |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.2% BSA |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2896927 |
Additional Formats
Product Specific Information
Recombinant rabbit monoclonal antibodies are produced using in vitro expression systems developed by cloning specific antibody DNA sequences from immunoreactive rabbits. Individual clones are screened to select the best candidates for production.
Advantages:
- Superior specificity and sensitivity
- Lot-to-lot consistency
- Animal origin-free formulation
- Broad immunoreactivity due to large rabbit immune repertoire
Target Information
CREB (Cyclic AMP response element binding protein) is a 43 kDa basic/leucine zipper transcription factor that binds the cyclic AMP response element (CRE) and activates transcription in response to extracellular signals such as neurotransmitters, hormones, membrane depolarization, and growth factors.
Activation of CREB depends on phosphorylation at serine 133 via p44/42 MAP kinase, p90RSK, p38 MAP kinase, and MSK1. Although CREB binds DNA regardless of phosphorylation, only the phosphorylated form functions as a transcription factor. CREB interacts with CREB binding protein (CBP) at the serine 133 region.
CREB is involved in:
- Circadian rhythm synchronization
- Adipocyte differentiation
- Learning and memory
In humans, the CREB gene is located on chromosome 2q. Dysregulation of CREB is associated with Alzheimer's disease, histiocytoma, and soft tissue melanoma.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
🏷️Thermo Fisher Scientific 상품 둘러보기
동일 브랜드의 다른 상품들을 확인해보세요
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-PTEN (Ser380, Thr382, Thr383) Recombinant Rabbit Monoclonal Antibody (PTENS380T382383-E4), PE
700,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-PTEN (Ser380, Thr382, Thr383) Recombinant Rabbit Monoclonal Antibody (PTENS380T382383-E4)
873,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-CREB (Ser133) Recombinant Rabbit Monoclonal Antibody (CREBS133-4D11), APC
265,000원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-CREB (Ser133) Recombinant Rabbit Monoclonal Antibody (CREBS133-4D11)
873,900원
Thermo Fisher Scientific
Thermo Fisher Scientific Phospho-CREB (Ser133) Recombinant Rabbit Monoclonal Antibody (CREBS133-4D11), PE
700,900원
배송/결제/교환/반품 안내
배송 정보
| 기본 배송비 |
| 교환/반품 배송비 |
|
|---|---|---|---|
| 착불 배송비 |
| ||
| 교환/반품 배송비 |
| ||
결제 및 환불 안내
| 결제수단 |
|
|---|---|
| 취소 |
|
| 반품 |
|
| 환급 |
|
교환 및 반품 접수
| 교환 및 반품 접수 기한 |
|
|---|---|
| 교환 및 반품 접수가 가능한 경우 |
|
| 교환 및 반품 접수가 불가능한 경우 |
|
교환 및 반품 신청
| 교환 절차 |
|
|---|---|
| 반품 절차 |
|