Thermo Fisher Scientific KDEL Receptor Pan Monoclonal Antibody (KR-10)
KDEL Receptor Pan Monoclonal Antibody (KR-10)은 다양한 종에서 KDEL 수용체를 검출할 수 있는 고특이성 항체입니다. Western blot, ICC/IF, IP에 사용 가능하며 단일클론 Mouse IgG1 형태로 제공됩니다. 연구용으로 4°C 또는 -20°C에서 안정적으로 보관 가능합니다.
- 판매단위
- pk
카탈로그
1개 옵션 · 카탈로그 번호를 클릭하면 복사됩니다Thermo Fisher Scientific · Thermo Fisher Scientific KDEL Receptor Pan Monoclonal Antibody (KR-10)
Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 1:1,000 | View 1 publication |
| Immunocytochemistry (ICC/IF) | 1:1,000 | - |
| Immunoprecipitation (IP) | 1:500 | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Bovine, Dog, Hamster, Human, Mouse, Non-human primate, Pig, Rabbit, Rat, Xenopus |
| Published Species | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | KR-10 |
| Immunogen | Synthetic peptide conjugated to KLH, corresponding to amino acids 192–212 of Cow KDEL Receptor |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein G |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_1956085 |
Product Specific Information
Store as a concentrated solution. Centrifuge briefly prior to opening vial.
Target Information
Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by continual retrieval from the cis-Golgi or a pre-Golgi compartment. Sorting of these proteins depends on a C-terminal tetrapeptide signal, typically lys-asp-glu-leu (KDEL) in animal cells and his-asp-glu-leu (HDEL) in S. cerevisiae.
This process is mediated by a receptor that recognizes and binds the tetrapeptide-containing protein and returns it to the ER. In yeast, the sorting receptor encoded by the single gene ERD2 is a seven-transmembrane protein.
In humans, several homologs of the ERD2 gene form the KDEL receptor gene family. The protein encoded by this gene was the first member identified and is structurally and functionally similar to the yeast ERD2 gene product.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
Thermo Fisher Scientific 상품 둘러보기
전체보기
문의
0개 · 배송·재고 문의는 실시간 상담이 빠릅니다아직 등록된 문의가 없어요.