Thermo Fisher Scientific CRHR1 Monoclonal Antibody (343919)
인간 CRHR1 단백질을 특이적으로 인식하는 Mouse IgG2a 단클론 항체. IHC 및 유세포분석(Flow Cytometry)에 사용 가능. 동결건조 형태로 제공되며, 재구성 후 0.5 mg/mL 농도 유지. 연구용으로만 사용.
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Applications
Immunohistochemistry (IHC)
- Tested Dilution: 8–25 µg/mL
Flow Cytometry (Flow)
- Tested Dilution: 2.5 µg per million cells
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 343919 |
| Immunogen | NS0 mouse myeloma cell line transfected with human CRHR-1 (Ser24–Val415) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 0.5 mg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS with 5% trehalose |
| Contains | No Preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2608931 |
Product Specific Information
This antibody detects human CRHR-1 transfectants but not irrelevant transfectants.
Reconstitute at 0.5 mg/mL in sterile PBS.
Target Information
Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors.
Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease.
Multiple isoforms of CRFR1 are produced by alternative splicing.
CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin.
ESTs have been isolated from human brain, eye, colon, and embryo libraries.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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