Thermo Fisher Scientific CRHR1 Monoclonal Antibody (343919)

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

8-25 µg/mL

-

Flow Cytometry (Flow)

2.5 µg per million cells

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG2a

Class

Monoclonal

Type

Antibody

Clone

343919

Immunogen

NS0 mouse myeloma cell line transfected with human CRHR-1 Ser24-Val415 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CRHR1,uniProtId:P34998-1,ncbiNodeId:9606,antigenRange:24-415,antigenLength:444,antigenImageFileName:MA5-24079_CRHR1_P34998-1_House_mouse.svg,antigenImageFileNamePDP:MA5-24079_CRHR1_P34998-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Lyophilized

Concentration

0.5 mg/mL

Purification

Protein A/G

Storage buffer

PBS with 5% trehalose

Contains

No Preservative

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2608931

Product Specific Information

This antibody detects human CRHR-1 transfectants but not irrelevant transfectants.

Reconstitute at 0.5 mg/mL in sterile PBS.

Target Information

Corticotropin-releasing factor receptor 1 (CRFR1/CRHR1), a Corticotropin-Releasing Factor Receptor, is involved in mediating the stress response and anxiety-related behaviors. Mutations of the receptor reduce anxiety-related behaviors and may be involved in the pathogenesis of Cushing disease. Multiple isoforms of CRFR1 are produced by alternative splicing. CRFR1 has been reported to be expressed in the pituitary, adrenal gland, brain, colon, ovary, placenta, testis, white blood cells, and skin. ESTs have been isolated from human brain, eye, colon, and embryo libraries.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.