Thermo Fisher Scientific Wilm`s Tumor 1 (WT1) (Wilm`s Tumor and Mesothelial Marker) Monoclonal Antibody (WT1/7450)
WT1 단백질을 인식하는 마우스 단클론 항체로, 인체 시료의 면역조직화학(IHC) 분석에 적합합니다. Recombinant WT1 단백질(aa150-350)을 면역원으로 사용하였으며, Protein A/G로 정제된 액상 형태입니다. 4°C 보관, 동결 금지.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: Assay-dependent
Immunohistochemistry (PFA fixed) (IHC (PFA))
- Tested Dilution: 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | WT1/7450 |
| Immunogen | Recombinant fragment (around aa150–350) of human WT1 protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C, do not freeze |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The Wilms Tumor 1 (WT1) gene encodes a WPP domain-interacting protein required for RanGAP nuclear envelope association in root tip cells. Ran GTPase is essential for nucleocytoplasmic transport, spindle formation, and postmitotic nuclear envelope reassembly. WT1 and WIT2 are CC-TMD proteins necessary for RanGAP nuclear envelope association, distinct from the WIP family.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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