Thermo Fisher Scientific OGDH Polyclonal Antibody
Human OGDH 단백질을 인식하는 Rabbit Polyclonal Antibody로, IHC 및 ICC/IF 실험에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성 제공. PBS 기반 저장용액으로 안정성 우수하며 연구용으로 사용 가능.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:20–1:50
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human OGDH. Recombinant protein control fragment (Product #RP-92648) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2789837 |
Product Specific Information
Immunogen sequence:
LRTCAAKLRP LTASQTVKTF SQNRPAAART FQQIRCYSAP VAAEPFLSGT SSNYVEEMYC AWLENPKSV
Target Information
This gene encodes one subunit of the 2-oxoglutarate dehydrogenase complex.
This complex catalyzes the overall conversion of 2-oxoglutarate (alpha-ketoglutarate) to succinyl-CoA and CO₂ during the Krebs cycle.
The protein is located in the mitochondrial matrix and uses thiamine pyrophosphate as a cofactor.
A congenital deficiency in 2-oxoglutarate dehydrogenase activity is believed to lead to hypotonia, metabolic acidosis, and hyperlactatemia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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