Thermo Fisher Scientific Thymidine Phosphorylase/PD-ECGF Recombinant Mouse Monoclonal Antibody (rTYMP, 3444)
Recombinant mouse monoclonal antibody against Thymidine Phosphorylase/PD-ECGF (rTYMP, 3444). Validated for WB and IHC(P). High purity Protein A/G purified, unconjugated liquid form. Suitable for human, mouse, and rat samples. For research use only.
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Applications
Western Blot (WB)
- Assay-dependent
Immunohistochemistry (Paraffin) (IHC (P))
- 1–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG1, kappa |
| Expression System | HEK293 cells |
| Class | Recombinant Monoclonal |
| Type | Antibody |
| Clone | rTYMP, 3444 |
| Immunogen | Recombinant full-length human Thymidine Phosphorylase (TP, PD-ECGF) protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Protein A/G |
| Storage Buffer | PBS, pH 7.4, with 0.05% BSA |
| Contains | 0.05% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
- For immunohistochemistry (PFA fixed), incubate antibody for 30 minutes at room temperature.
- Staining of formalin-fixed tissues requires heating sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 minutes at 95°C, followed by cooling at room temperature for 20 minutes.
Target Information
Thymidine Phosphorylase (TP), also known as platelet-derived endothelial cell growth factor (PD-ECGF) or gliostatin, catalyzes the reversible phosphorolytic cleavage of thymidine and deoxyuridine to their corresponding bases and 2-deoxyribose-1-phosphate. It acts as a chemotactic and mitogenic factor for endothelial cells and is a non-heparin binding angiogenic factor found in platelets. TP is also involved in converting fluoropyrimidines, cytotoxic agents used in cancer therapy, into active metabolites.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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