Thermo Fisher Scientific TAOK2 Polyclonal Antibody
TAOK2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot에 적합하며 인간, 마우스, 랫트 시료에 반응. Affinity chromatography로 정제된 고품질 항체로, TAO2의 내인성 수준 검출에 사용 가능.
- 판매단위
- pk
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Thermo Fisher Scientific TAOK2 Polyclonal Antibody
Applications
- Western Blot (WB)
Tested Dilution: 1:500–1:2,000
Species Reactivity
- Human
- Mouse
- Rat
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human TAOK2 (Accession Q9UL54), corresponding to amino acid residues A559–K609 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Wet ice |
| RRID | AB_2903306 |
Product Specific Information
Antibody detects endogenous levels of total TAO2.
Target Information
TAOK2 (TAO1) is a serine/threonine kinase that may regulate the stress-responsive p38 MAP kinase pathway. In vitro, TAO2 activates MAP/ERK kinases (MEK) 3, 4, and 6 toward their substrates p38 MAP kinase and JNK/SAPK (Chen et al., 1999; Chen and Cobb, 2001).
Research suggests TAO protein kinases play an essential role in signaling from physiological agonists to the p38 MAPK pathway (Chen et al., 2003).
Autophosphorylation of TAO may contribute to activation mechanisms, with Ser181 located within the MEK binding domain.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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