Thermo Fisher Scientific Human CAMKK1 (CAMKKA), His Tag Recombinant Protein
Human CAMKK1 (CAMKKA) recombinant protein with His-tag, expressed in baculovirus system. Suitable for kinase assay research. Full-length purified form with high stability in glycerol-based buffer. For research use only, not for diagnostic or resale.
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Applications
- Kinase Assay (KA): Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species | Human |
| Expression System | Baculovirus |
| Amino Acid Sequence | Full length |
| Tag | His-tag |
| Molecular Weight | 59.8 kDa |
| Class | Recombinant |
| Type | Protein |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Purified |
| Storage Buffer | 50 mM Tris, pH 7.5, with 0.5 mM EDTA, 50% glycerol, 2 mM DTT, 0.02% Triton X-100, 150 mM NaCl |
| Contains | No preservative |
| Storage Conditions | -80°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Dry ice |
Product Specific Information
For maximum recovery, please spin prior to use.
Aliquots of 5 µg, 10 µg, and 20 µg sizes are not recommended—use original packaging until exhausted.
For larger sizes, aliquoting can reduce freeze/thaw cycles; avoid aliquots below 20 µL.
Do not store kinase diluted.
Properly stored at -80°C, guaranteed for 6 months from purchase date.
Protein Form: Full Length
Target Information
CAMKK1 (CAMKKA) is a serine/threonine protein kinase belonging to the Ca²⁺/calmodulin-dependent kinase subfamily.
CaMKKα is part of the nuclear factor of activated T cells (NFAT) transcription complex, which includes cytosolic and nuclear components activated upon T cell receptor stimulation.
This kinase family regulates inducible gene transcription during immune responses and serves as a molecular target for immunosuppressive drugs such as cyclosporin A.
Five transcript variants encoding distinct isoforms have been identified, potentially regulating expression of different cytokine genes.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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