Thermo Fisher Scientific BPNT1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human BPNT1. Recombinant protein control fragment (Product #RP-94410). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:BPNT1,uniProtId:O95861-1,ncbiNodeId:9606,antigenRange:79-161,antigenLength:308,antigenImageFileName:PA5-61743_BPNT1_O95861-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61743_BPNT1_O95861-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638586

Product Specific Information

Immunogen sequence: SEEVDQELIE DSQWEEILKQ PCPSQYSAIK EEDLVVWVDP LDGTKEYTEG LLDNVTVLIG IAYEGKAIAG VINQPYYNYE AGP

Highest antigen sequence identity to the following orthologs: Mouse - 94%, Rat - 92%.

Target Information

BPNT1, also called bisphosphate 3-prime-nucleotidase, or BPntase, is a member of a magnesium-dependent phosphomonoesterase family. Lithium, a major drug used to treat manic depression, acts as an uncompetitive inhibitor of BPntase. The predicted human protein is 92% identical to mouse BPntase. BPntase`s physiologic role in nucleotide metabolism may be regulated by inositol signaling pathways. The inhibition of human BPntase may account for lithium-induced nephrotoxicity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.