Thermo Fisher Scientific HGF Polyclonal Antibody
인간 HGF 단백질을 인식하는 염소 유래 폴리클로날 항체. Western blot 및 IHC(P) 실험에 적합. 항원 친화 크로마토그래피로 정제된 액상 형태. 세포 성장과 이동, 형태형성 연구용. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.1–0.2 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 15 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant human HGF (rhHGF) expressed in SF21 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 5% trehalose |
| Contains | No preservative |
| Storage Conditions | Store at 4°C short term. For long term, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2118757 |
Product Specific Information
Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Hepatocyte growth factor (HGF) regulates cell growth, motility, and morphogenesis through activation of the c-Met receptor tyrosine kinase signaling cascade. It is secreted by mesenchymal cells and acts as a multifunctional cytokine on epithelial cells. HGF stimulates mitogenesis, cell motility, and matrix invasion, playing central roles in angiogenesis, tumorigenesis, and tissue regeneration. The inactive single-chain precursor is cleaved into a 69-kDa alpha-chain and a 34-kDa beta-chain, linked by a disulfide bond to form the active heterodimeric molecule. Although it belongs to the plasminogen subfamily of S1 peptidases, it has no detectable protease activity. Alternative splicing generates multiple isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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