
Thermo Fisher Scientific POLR2B Polyclonal Antibody
Rabbit polyclonal antibody against human POLR2B for Western blot and immunoprecipitation. Recognizes RNA polymerase II subunit involved in mRNA synthesis. Affinity purified, supplied in PBS with ProClin 300, and stored at -20°C.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunoprecipitation (IP) | 1–5 µL/mg of lysate |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived Human POLR2B fragment |
| Conjugate | Unconjugated |
| Form | Liquid |
| Purification | Antigen affinity chromatography, Protein A |
| Storage Buffer | PBS, pH 7 |
| Contains | 0.03% ProClin 300 |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2902773 |
Target Information
The POLR2B gene encodes the second largest subunit of RNA polymerase II, which is responsible for synthesizing messenger RNA in eukaryotes. This subunit, along with at least two other polymerase subunits, forms a structure that maintains contact between the DNA template and the newly synthesized RNA within the enzyme’s active site.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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