Thermo Fisher Scientific LYRM1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human LYRM1. Recombinant protein control fragment (Product #RP-106966). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LYRM1,uniProtId:O43325-1,ncbiNodeId:9606,antigenRange:1-61,antigenLength:122,antigenImageFileName:PA5-66281_LYRM1_O43325-1_Rabbit.svg,antigenImageFileNamePDP:PA5-66281_LYRM1_O43325-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2662103

Product Specific Information

Immunogen sequence: MTTATRQEVLG LYRSIFRLAR KWQATSGQME DTIKEKQYIL NEARTLFRKN KNLTDTDLIK

Highest antigen sequence identity to the following orthologs - mouse 87%, rat 92%.

Target Information

LYRM1 was one of many genes identified through a suppression subtractive hybridization comparing their expression in omental adipose tissue of obese patients compared to non-obese individuals. Further study confirms that both mRNA and protein levels of LYRM1 are higher in obese individuals. LYRM1 is widely expressed, with highest levels occurring in adipose and liver tissues. It is thought that LYRM1 promotes preadipocyte proliferation and can inhibit apoptosis of preadipocytes. Ectopic LYRM1 expression did not significantly affect adipogenesis, suggesting that LYRM1 can influence adipose tissue homeostasis by modulating the size of the preadipocyte pool.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.