
Thermo Fisher Scientific CHD9 Polyclonal Antibody
CHD9 단백질을 검출하는 Rabbit Polyclonal Antibody로 Western Blot 및 Immunohistochemistry(Paraffin)에 적합합니다. 인간 및 생쥐 반응성, 액상 형태로 제공되며 Affinity Chromatography로 정제되었습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- PA5103742
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000–1:3,000
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human CHD9 (Accession Q3L8U1), corresponding to amino acid residues I1450–K1500 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4, with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2853075 |
Product Specific Information
Antibody detects endogenous levels of total CHD9.
Target Information
CHD9 (chromodomain-helicase-DNA-binding protein 9), also known as chromatin-related mesenchymal modulator (CReMM), PPAR-α-interacting complex protein, kismet homolog 2, or CHROM1, is a 2,897 amino acid protein belonging to the Snf2/Rad54 helicase family.
The CHD family of proteins are ATP-dependent chromatin remodeling enzymes combining chromodomains with SWI2/Snf2 ATPase/helicase motifs and DNA-binding capability.
Localized to the cytoplasm and nucleus, CHD9 contains two chromodomains, one ATP-binding helicase domain, and one C-terminal helicase domain.
Chromodomains are conserved regions (~40–50 amino acids) found in proteins associated with chromatin remodeling and manipulation across plants and animals.
CHD9 acts as a transcriptional coactivator for PPARα and may also function as an ATP-dependent chromatin remodeling protein.
CHD9 is widely expressed at low levels and exists as three isoforms produced by alternative splicing.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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